Functional Groups of Interest
Nonpolar
| Alkane |
Alkene |
Alkyne |
Benzene |
| \(pK_a=50\) |
\(pK_a=44\) |
\(pK_a=25\) |
|
|
|
|
|
Polar - Benzene
| Phenol |
Aniline |
Toluene |
| \(pK_a=9.98\) |
\(pK_b=9.37\) |
|
|
|
|
Polar - OX
|
Alcohol |
Ether |
Ketone |
Aldehyde |
Carboxylic Acid |
Acid Anhydride |
Ester |
Acyl Halide |
|
\(pK_a=16\) |
|
|
|
pK_a=4.8 |
|
|
|
| \(1^\circ\) |
|
|
|
|
|
|
|
|
| \(2^\circ\) |
|
|
|
|
|
|
|
|
| \(3^\circ\) |
|
|
|
|
|
|
|
|
Polar - N
|
Amine |
Azo Compound |
| \(pK_a=38\) |
|
|
| \(1^\circ\) |
|
|
| \(2^\circ\) |
|
|
| \(3^\circ\) |
|
|
| \(4^\circ\) |
|
|
Polar - O/N
| Amide |
Nitro |
Imide |
Isocyanate |
|
|
|
|
Polar - Other
| Alkyl Halide |
Sulfhydryl/Thiol |
Disulfide |
| \(pK_a=−7\) |
\(pK_a=7\) |
|
|
|
|
