2018¶

Synthesis 1 (AS02) 1 from 0 (attempt 2)¶

Today I started the synthesis of 1 from 0. The details were:

In a 50 mL two neck round bottom flask, 101.6 mg of 0 was dissolved in 20 mL of acetic acid. With constant stirring, 86 mg of hexylamine ($\ce{H2N-C6H13}$) was added dropwise to the acetic acid. The flask was then capped and refluxed at 120$^\circ$ C$ for two hours before being removed from the heat off and left at room temperature with stirring over the weekend.

Notes¶

TLC was not run, as acetic acid is very polar and prevents the rest of the compounds from migrating individually.